Gamete Activation Media

Oocyte and Sperm Activation Media

GM508 CultActive Oocyte Activation

GM508 Cult Active is a bicarbonate-buffer­ed reagent designed to investigate oocytes of patients with failed fertilization after previous Intracytoplasmatic Sperm Injection cycles.  GM508 CultActive is designed to investigate if fertilization failure after previous ICSI-cycles is due to a deficient oocyte activation.

Composition

  • NaCl, KCl, KH2PO4, MgSO4.7H2O, NaHCO3, CaCl2.2H2O, D(+)-Glucose anhydrous, Na-Lactate, Na-Pyruvate, EDTA, Alanyl-Glutamine, water, non-essential and essential Amino Acids, DMSO, Ca2+-Ionophore A23187.

Specification and Quality Control

  • All raw materials are of highest available purity (European Pharmacopoeia and/or USP standard) if applicable.
  • A certificate of analysis is available for each batch upon request from our website with respective lot number.
    The MSDS for GM508 CultActive is available upon request.
  • GM508 CultActive is manufactured and tested according to the following specifications:
pH (at 37°C, 6 % CO2) 7.00-7.60
Osmolality (mOsm/kg) 400-450
Sterility sterile – SAL 10-3 (Sterility Assurance Level)
Endotoxins (EU/ml) < 0.25
MEA (Blastocysts after 96h in %)  ≥ 80

Ordering Information

Product description Product code Unit
GM508 CultActive 4 GM 508CULT-active1 1 ml

GM501 SpermMobil Sperm Activation

GM501 SpermMobil is a HEPES-buffered reagent containing low bicarbonate. It is used for in-vitro examination of sperms of necrozoospermic ejaculates as well as of immotile sperms isolated from testicular tissue (TESE).

Composition

  • Theophylline solved in HEPES-buffered medium.
  • NaCl, KCl, KH2PO4, MgSO4.7H2O, NaHCO3, CaCl2.2H2O, D(+)-Glucose Anhydrous, Na-Lactate, Na-Pyruvate, EDTA, Alanyl-Glutamine, water, non-essential and essential Amino Acids, Phenolred, HEPES, Theophylline

Product specifications and quality control:

  • All raw materials are of highest available purity (European Pharmacopoeia and/or USP standard) if applicable.
  • A certificate of analysis is available for each batch upon request from our website with respective lot number.
  • The MSDS for GM501 SpermMobil is available upon request
  • GM501 SpermMobil is manufactured and tested according to the following specifications:
pH (at 37°C) 7.20-7.60
Osmolality (mOsm/kg) 280-320
Sterility sterile – SAL 10-3 (Sterility Assurance Level)
Endotoxins (EU/ml) < 0.50
Sperm Survival test – survival after 45 minutes exposure of density selected spermatozoa to the test medium ≥ 80%
Product description Product code Unit
GM501 SpermMobil 4 GM 501SMOBIL-5 5 ml
GM501 SpermMobil 4 GM 501SMOBIL-1 1 ml

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